Mounjaro (Tirzepatide) is a novel type 2 diabetes medication with weight loss effects even in non-diabetics. Like any other drug, Mounjaro can cause some side effects, which are mostly only temporary. If you have been prescribed this medicine, it’s important to know what to expect, especially after the first injection.

Below, we’re going to walk you through different types of Mounjaro side effects and how to manage them. In the end, you can decide whether the Mounjaro benefits are worth the nausea, constipation, diarrhea, body aches, etc.

What Does Mounjaro Do to Your Body?

As a diabetes drug, Mounjaro injection lowers the blood sugar level, determined by a reduction in HbA1c. Fat loss is also facilitated because of the side effects from Mounjaro. We have already discussed Mounjaro for weight loss and the mechanism by which this medicine promotes insulin production in the body at Elegant Hoopoe. However, there is still more to share with you about how it can benefit you and your body.

What Are Mounjaro Benefits?

As mentioned before, Mounjaro injections play an important role in type 2 diabetes management and weight reduction. However, it’s been established that this drug also alleviates health problems such as heart failure and liver conditions. Because of the improved quality of life, patients on Mounjaro tend to sleep better. In the next paragraphs, we’ll answer a few common questions about Mounjaro benefits for weight loss.

Is Mounjaro Effective for Weight Loss?

Mounjaro has a noticeable effect on weight loss. Clinical trials have shown that those who used Mounjaro experienced significant reductions in body weight. For example, in a study published in JAMA, participants had a mean weight reduction of 20.9% in 36 weeks. Another trial reported an average weight loss of 15.7% in overweight or obese adults. These findings suggest that Mounjaro can be a fairly effective option for weight management.

Why Aren’t You Losing Weight with Mounjaro Effects?

If you are not losing weight while using Mounjaro, it can be a result of several factors: 

Caloric Intake: Even with a reduced appetite, if you consume more calories than you burn, it can slow weight loss. 

Physical Activity: Not having an active lifestyle can slow your metabolism and make your weight loss more challenging. 

Consistency and dosage: Inconsistent use of Mounjaro or incorrect dosing can reduce its effectiveness. 

Medical Conditions: Conditions like hypothyroidism or insulin resistance can slow down your weight loss efforts.

A woman laughing with a Mounjaro injection pen in her hand

What Are the Most Common Side Effects of Mounjaro Shot?

As a patient about to start taking Mounjaro, you have every right to wonder what the side effects of Mounjaro are. Based on drugs.com and WebMD.com, possible side effects of Mounjaro injection include gastrointestinal issues such as nausea, vomiting, diarrhea, loss of appetite, indigestion, constipation, and stomach pain.

Additional Mounjaro injection side effects include:

  • headaches
  • dizziness
  • body aches
  • depression
  • fatigue
  • Mounjaro injection site redness and reactions
  • rare cases of low blood sugar (especially when combined with insulin or sulfonylureas)

In severe cases, pancreatitis or gallbladder issues may occur. Symptoms are typically mild and improve over time. In case of persistent or severe reactions, consult your healthcare provider.

Mounjaro Side Effects: Hair Loss

Hair loss is not on the list of common Mounjaro injection side effects. However, clinical trials have reported that approximately 4.9% to 5.7% of individuals who took Mounjaro in those studies, experienced hair loss. This hair loss is often temporary and might be due to rapid weight loss, which can cause a condition called telogen effluvium—a temporary disruption in the hair growth cycle.

Mounjaro Long-Term Side Effects

Even though rare, some side effects caused by Mounjaro treatment can go on for a while. If that’s the case for you, you may need to start receiving proper medication to relieve these Mounjaro long-term effects, like digestive issues, or treat pancreatitis. According to Mounjaro injection reviews, symptoms like throwing up and diarrhea are more common side effects among Mounjaro users, but they shouldn’t last more than 2 days. Otherwise, it can lead to kidney failure. If so, report the problem to a doctor.

How Long After Mounjaro Injection Do Side Effects Start?

Patients who want to begin their Mounjaro routine are usually anxious about when Mounjaro’s side effects start. According to Mounjaro side effects reviews on Reddit, people often report the absence of any considerable side effects, especially on lower doses. However, some mild discomforts can still appear such as headaches, burping, reduced appetite, digestive problems, and fatigue within the first few hours after the injection.

So instead of asking “When do you feel Mounjaro side effects?”, you should be more concerned about whether or not you’ll feel any of its side effects. If there’s going to be any symptoms, they usually kick in within a couple of days. The very first injection is when most of the Mounjaro medication side effects occur but once the body is used to the medicine, you will feel almost nothing. Also, Mounjaro complications are more likely when you increase your dose. That’s why you should make sure to pay attention to the Mounjaro dosing guide and start with 2.5 mg for at least the first month to allow the body to adjust to Mounjaro.

How Long Does Mounjaro Side Effect Last?

The side effects are usually mild to moderate and often seen during the initial stages of treatment or when increasing the dosage. Normally, they go away within a few weeks as your body adjusts to the medication. However, some individuals may experience gastrointestinal issues for a longer period. If the side effect of Mounjaro persists or gets worse, consult your healthcare provider.

What Are the Serious Side Effects of Mounjaro?

Mounjaro and Cancer

Mounjaro manufacturer claims that taking Mounjaro could carry some serious risks, including the potential for thyroid C-cell tumors (only in animal studies), but this cancer risk in humans is unclear. Therefore, it is not recommended for individuals with a personal or family history of thyroid cancer

Other Risks of Mounjaro Injection

Other risks include pancreatitis (severe abdominal pain), gallbladder issues, and rare allergic reactions like difficulty breathing. You can discuss these risks with your doctor to see if Mounjaro is right for you.

Happy woman holding a question mark in one hand and a Mounjaro pen in another hand

How to Reduce Mounjaro Side Effect?

You need to employ a different approach based on the type of side effect you experience with Mounjaro injections. Here’s a full guide about how to deal with Mounjaro drug side effects in different cases:

Nausea and Vomiting

  • Drink more water and other fluids.
  • Don’t continue eating when you feel full.
  • Eat bland foods like white rice, white bread, plain pasta, boiled potatoes, crackers, fruit juice, etc. which are usually soft, not fried, not spicy, and low in fiber.
  • Eating foods or drinking fluids containing ginger and peppermint.
  • Avoid eating food with strong smells.
  • Eat small regular meals.
  • Cut back on sugar and fatty foods.
  • Go outside to get fresh air.

Constipation

  • Go on regular walks.
  • Keep yourself hydrated with enough fluid intake.
  • Take a walk regularly to stay physically active.
  •  Eat more fiber-rich foods such as vegetables and whole carbohydrates.
  • Eat small frequent meals.
  • Avoid alcohol.

Headaches

  •  Enough fluid intake.
  •  Access to a quiet environment where you can rest.
  • Relaxation treatments like messages or meditation.
  • Regular physical activity.
  • Good quality sleep.

Diarrhea

  •   Drink plenty of liquids.
  • Avoid caffeine, fruit juices, and alcohol.
  • Getting enough rest during the day.

Burping

  • Try to eat more slowly.
  • Avoid using a straw.
  • Drink at least 8 glasses of water during the day.
  • Exercise.
  • Inject Mounjaro during your meal.
  • Avoid alcohol and carbonated drinks.

Mounjaro Side Effects Overview

Some mild to moderate side effects are possible when you’re taking Mounjaro. They usually happen after your first few injections or when you intend to increase your Mounjaro dose. However, not everyone experiences these tirzepatide injection side effects. 

The symptoms often include vomiting, nausea, heartburn, headaches, tiredness, or body aches, and they usually don’t last more than a few weeks. So there’s nothing to worry about. Knowing about the common side effects of Mounjaro helps you prepare for what’s coming. Feel free to reach out to us at Elegant Hoopoe if you have any questions about our Mounjaro weight loss treatments and how to manage Mounjaro side effects with simple steps. 

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